Product Information
- 02-0201 Anti 8-OHdG monoclonal antibody (100µg)
- 02-0202 Anti 8-OHdG monoclonal antibody (20µg)
Oxidative Stress
Anti 8-OHdG monoclonal antibody
Tagged 8-OH-dG, DNA Oxidation, Oxidative Stress
Anti-Dityrosine (DT) monoclonal antibody
About Dityrosine: A novel biomarker for protein oxidation
Tyrosine is one of the major targets of protein oxidation, and until today various tyrosine derivatives such as nitrotyrosine, dityrosine (DT) and halogenated tyrosine depending on the type of free radicals. DT is a tyrosine dimer derived from tyrosyl radicals which is formed by reactive oxygen species (ROS), metal-catalyzed oxidation, ultraviolet irradiation, and peroxidases. Dityrosine have been found in atherosclerotic lesions, and lipofuscin of pyramidal neurons of aged human brains. Dityrosine is one of the specific biomarkers for protein oxidation.
Dityrosine A novel biomarker for protein oxydation
Product Information
- 02-0601: Anti-DiTyrosine (DT) monoclonal antibody
Tagged Dityrosine, Oxidative Stress, protein oxidation
Anti-Dibromo-Tyrosine (DiBrY) monoclonal antibody
About Dibromo-Tyrosine
Neutrophils and eosinophils play an important role in the defence system against microbial infection. Myeloperoxidase (MPO) and eosinophil peroxidase (EPO) are known to catalyze formation of hypochlorous acid (HOCl) and hypobromous acid (HOBr). These reactive intermediates may react with proteins, lipids and nucleotides, and it has been reported to form tyrosine halogenation such as dibromotyrosine (DiBrY). DiBrY is a Br-modified tyrosine at 3- and 5- position, which is one of the major oxidative products derived from neutrophil myeloperoxidase.
Formation of Dibromo-Tyrosine
Product Information
- 02-0401: Anti-Dibromo-Tyrosine (DiBrY) monoclonal antibody (20µg)
Anti-Tymidine Glycol (TG) Monoclonal Antibody
About Thymidineglycol: A DNA oxidation marker
Thymidineglycol (TG) is one of the major oxidation products of DNA. Thymidine (T) can be damaged by oxidative stress such as radiation and energy metabolism. Two different pathways to form TG have been suggested. Deoxythymidine in DNA is directly oxidised by hydroxy radical, to form TG. TG can be also formed through an intermediate thymidine chlorohydrin, which is derived from hypochlorous acid (HOCl) from neutrophil myeloperoxidase. Thymidineglycol is derived from DNA, not from RNA. TG is the oxidative stress marker secific for DNA damage.
Thymidineglycol formation process
Product Information
- 02-0501: Anti-Thymidineglycol (TG) monoclonal antibody (20µg)
Anti-4-HNE monoclonal antibody
Product Information
- 02-0301 Anti 4-HNE monoclonal antibody (100µg)
- 02-0302 Anti 4-HNE monoclonal antibody (20µg)
Tagged 4-HNE, lipid peroxydation, Oxidative Stress
