8-hydroxy-2′-deoxyguanosine (8-OHdG) is a product of oxidatively damaged DNA formed by hydroxy radical, singlet oxygen and direct photodynamic action. 8-OHdG can be detected in tissue, serum, urine and other biomaterials. 8-OHdG Check is a competitive enzyme-linked immunosorbent assay (ELISA) utilising monoclonal antibody (clone N45.1) which is highly specific for DNA damage, not cross react with RNA oxidation products such as 8-hydroxy-guanine and 8-hydroxy-guanosine. This product is suitable for detection of 8-OHdG in urine and other biomaterials from human and animals.
Formation of 8-hydroxy-2'-deoxyguanosine (8-OHdG) by oxygen radicals. H Kasai Environmental Mutagen Research, Vol 10, p73-78(1988)
This product is a 8-OHdG ELISA kit utilizing anti 8-OHdG monoclonal antibody (clone N45.1) which is highly specific for 8-OHdG. We provide two types of 8-OHdG ELISA kits with different assay range. New 8-OHdG Check ELISA is suitable for urine and serum sample from animal and human. If you are planning to measure 8-OHdG in human serum,tissue, cultured cells, we recommend to use ‘Highly Sensitive 8-OHdG Check ELISA.
- High specificity & high sensitivity: Cross reactivity was checked for 19 analogues.
- Easy operation & speedy: There is no need for expensive equipment and sample pretreatment. Required equipments are: pipettes, incubator and micro plate reader with 450nm filter. Assays can be completed within 3.5 hours (New 8OHdG Check).
Product Information
- 02-0101: 8-OHdG Check ELISA kit
- 02-0102: Highly Sensitive 8-OHdG Check ELISA kit
- 02-0103: 8-OHdG Check ELISA Trial Package (32wells)
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