lipid peroxydation

Anti-7-Ketocholesterol (7-KC) monoclonal antibody

mars 10  |  Oxidative Stress, Products  |   admin

About 7-ketocholesterol

Cholesterol oxidation products, especially 7-Ketocholesterol (7KC), have been the focus of much attention because they are present in human atherosclerotic plaque and display a wide range of atherogenic properties in vitro and to some extant in vivo. This antibody is specific for 7KC. This antibody is useful to detect 7KC in tissue samples. A frozen tissue sample is recommended for immunohistochemistry.

7-Ketocholesterol

Product Information

  • 02-1301: Anti 7-ketocholesterol (7-KC) monoclonal antibody (20µg)

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Anti-Methyglyoxal (MG) monoclonal antibody

mars 10  |  Oxidative Stress, Products  |   admin

About Methyglyoxal (MG)

Methylglyoxal (MG), an endogenous metabolite that increases in diabetes and is a common intermediate in the Maillard reaction (glycation), reacts with proteins and forms advanced glycation end products (AGE). MG reacts with arginine residue in protein and forms numerous numbers of adducts, such as argpyrimidine. This antibody is specific for argpyrimidine: N-(5-hydroxy-4,6-dimethylpyrimidine-2-yl)-L-ornithine.

Methylglyoxal Adduct

Product Information

  • 02-1201: Anti-methylglyoxal monoclonal antibody

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Anti-Crotonaldehyde (CRA) monoclonal antibody

mars 10  |  Oxidative Stress, Products  |   admin

About crotonaldehyde (CRA)

Crotonaldehyde (CRA) is a representative carcinogenic aldehyde formed endogenously through lipid peroxidation. CRA is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with CRA and lysine residue leads to the formation of numerous numbers of adducts. This antibody is specific for the CRA-modified protein.

Crotonaldehyde

Product Specification

  • 02-1101: Anti-Crotonaldehyde (CRA) monoclonal antibody (30µg)

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Anti-4-hydroxy-2-hexenal (4-HHE) monoclonal antibody

mars 10  |  Oxidative Stress, Products  |   admin

About 4-hydroxy-2-hexenal (4-HHE)

4-hydroxy-2-alkenal is one of the major lipid peroxidation products, and shows many biological effects such as high toxicity to cells. Among them, 4-hydroxy-2-hexenal (HHE) is an aldehyde formed during peroxidation of n-3 fatty acids such as docosahexaenoic acid. HHE is highly reactive aldehyde and reacts with histidine residue of protein to form Michael-addition type adducts. This antibody is specific for HHE-histidine Michael adduct (HHE-His) and enable to detect HHE-His in the tissue samples.

4-hydroxy-2-hexenal adduct

Product Information

02-1001: Anti-4-hydroxy-2-hexenal (4-HHE) monoclonal antibody (30µg)

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Anti-Acrolein (ACR) monoclonal antibody

mars 10  |  Oxidative Stress, Products  |   admin

About Acrolein (ACR)

Acrolein (ACR) is a representative carcinogenic aldehyde found ubiquitously in the environment and formed endogenously through oxidation reactions, such as lipid peroxidation and myeloperoxidasecatalyzed amino acid oxidation. ACR is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with ACR and lysine residue leads to the formation of numerous numbers of adducts, such as formyl-dehydropiperidino-lysine (FDP-lysine) type derivative. This antibody is specific for the ACR-modified protein, especially FDP-lysine type derivative.

Acrolein Adduct

Product Information

  • 02-0901: Anti-Acrolein (ACR) monoclonal antibody (20µg)

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Anti-malondialdehyde (MDA) monoclonal antibody

mars 10  |  Oxidative Stress, Products  |   admin

About malondialdehyde (MDA)

Malondialdehyde (MDA) is one of the major aldehyde derive from lipid peroxidation. MDA is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with MDA and lysine residue leads to the formation of numerous numbers of adducts, such as dihydropyridine-lysine (DHP-lysine) type derivative. This monoclonal antibody is specific for the MDA-modified protein, especially DHP-lysine type derivative.

Malondialdehyde adduct

Product Information

  • 02-0801: Anti-Malonaldehyde antibody (30µg)

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Anti-4-HNE monoclonal antibody

février 24  |  Oxidative Stress, Products  |   admin

Product Information

  • 02-0301 Anti 4-HNE monoclonal antibody (100µg)
  • 02-0302 Anti 4-HNE monoclonal antibody (20µg)

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